Corticosteroids increase oxidative stress which impairs the phagocytic (debris clearing) ability of cells in the eye’s drainage system. Corticosteroids in the form of eye drops, creams, pills, inhalers and injections are a common trigger, since these drugs polymerize molecules in the drainage system of the eye, while inhibiting the formation and repair of collagen and glycosaminoglycans necessary for maitaining normal structure and function of both the eye’s lamina cribrosa and the trabecular meshwork. Even the preservatives used in many eye drops, including most glaucoma medications, may trigger chronic inflammation of the eye that can worsen glaucoma. Several investigators have demonstrated that PGE 2 and PGF 2 alpha in low doses, lower intraocular pressure in all species studied, including human, but while PGF 2 promotes inflammation that could aggravate glaucoma, PGE 2 has anti-inflammatory effects. Other effective alternatives for relief of pain and inflammation include a highly absorbable water soluble quercetin (Pain Guard forte').

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Beta blocker eye drops can reduce IOP somewhat (6 mm Hg, preventing further loss of peripheral vision for 3 to 6 years), but do not improve blood flow to the eyes. The risk factors that affect glaucoma are generally those associated with vascular problems, including hypertension, hypotension, migraine, increased blood viscosity, carotid artery stenosis, heart disease, and even a familial tendency, which is true of vascular disease in general. Low tension glaucoma is also associated with peripheral and central vasoconstriction (e.g. migraine) and spontaneous blood clots. Beta blocker drops commonly cause side effects including: low blood pressure, chat free porn confusion, depression, dizziness, headache, impotence, hair loss, skin and nail changes, diarrhea, nausea, asthma, breathing difficulty, chat free porn and increased LDL cholesterol. Benzalkonium chloride used to preserve Timoptic, Betoptic, Optipranolol, and Ocupress anti-glaucoma drops increases dry eye symptoms by 250%. Merck manufactures an unpreserved beta blocker eye drop called OcuDose. Beta blocker eye drops used for glaucoma have other serious implications for body chemistry.